Centers around a group of college kids as they are driving on an unfamiliar road. Everything seems fit for a road trip to the lake but, when the group accidentally runs over an unsuspecting squirrel, they quickly realize there will be a price to pay. The cursed road brings the zombie squirrel back to life to terrorize the kids. After the kids crash and everyone is injured except the younger brother, he is forced to set out on a journey to defeat the ancient curse and save his brother and friends before it is too late.